Poly(ADP-Ribose) Glycohydrolase (PARG) vs. Poly(ADP-Ribose) Polymerase (PARP) – Function in Genome Maintenance and Relevance of Inhibitors for Anti-cancer Therapy
Poly(ADP-ribose) polymerases (PARPs) are a family of enzymes that catalyze the addition of poly(ADP-ribose) (PAR) subunits onto themselves and other acceptor proteins. PARPs are known to function in a large range of cellular processes including DNA repair, DNA replication, transcription and modulati...
Asıl Yazarlar: | , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2020-08-01
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Seri Bilgileri: | Frontiers in Molecular Biosciences |
Konular: | |
Online Erişim: | https://www.frontiersin.org/article/10.3389/fmolb.2020.00191/full |