Antiretroviral Drug-Resistance Mutations on the <i>Gag</i> Gene: Mutation Dynamics during Analytic Treatment Interruption among Individuals Experiencing Virologic Failure

Antiretroviral Drug-Resistance Mutations on the <i>Gag</i> Gene: Mutation Dynamics during Analytic Treatment Interruption among Individuals Experiencing Virologic Failure

We describe drug-resistance mutation dynamics of the <i>gag</i> gene among individuals under antiretroviral virologic failure who underwent analytical treatment interruption (ATI). These mutations occur in and around the cleavage sites that form the particles that become the mature HIV-1...

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Bibliographic Details
Main Authors: James R. Hunter, Domingos E. Matos dos Santos, Patricia Munerato, Luiz Mario Janini, Adauto Castelo, Maria Cecilia Sucupira, Hong-Ha M. Truong, Ricardo Sobhie Diaz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pathogens
Subjects:
antiretroviral virologic failure
antiretroviral resistance
analytical treatment interruption
fitness cost
<i>gag</i> gene
Online Access:https://www.mdpi.com/2076-0817/11/5/534

Internet

https://www.mdpi.com/2076-0817/11/5/534

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