Heparin-induced thrombocytopenia: a rare presentation with skin necrosis

Heparin-induced thrombocytopenia is the most clinically relevant non-haemorrhagic complication of heparin and is characterised by the presence of anti-PF4/heparin-IgG antibodies. The circulating PF4/heparin-IgG immune complex binds to platelets via their FcyIIa receptors, activating them and promot...

Full description

Bibliographic Details
Main Authors: Filipa David, Ana Catarina Trigo, José Ribeiro, Joana Cancela
Format: Article
Language:English
Published: PAGEPress Publications 2023-10-01
Series:Dermatology Reports
Subjects:
Online Access:https://www.pagepress.org/journals/index.php/dr/article/view/9855