Apoptosis and oxidative stress as relevant mechanisms of antitumor activity and genotoxicity of ZnO-NPs alone and in combination with N-acetyl cysteine in tumor-bearing mice

Apoptosis and oxidative stress as relevant mechanisms of antitumor activity and genotoxicity of ZnO-NPs alone and in combination with N-acetyl cysteine in tumor-bearing mice

Haidan M El-Shorbagy, Shaymaa M Eissa, Salwa Sabet, Akmal A El-GhorDepartment of Zoology, Faculty of Science, Cairo University, Giza, EgyptBackground: Several in vitro studies have revealed that zinc oxide nanoparticles (ZnO-NPs) were able to target cancerous cells selectively with minimal damage to...

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Bibliographic Details
Main Authors: El-Shorbagy HM, Eissa SM, Sabet S, El-Ghor AA
Format: Article
Language:English
Published: Dove Medical Press 2019-05-01
Series:International Journal of Nanomedicine
Subjects:
ZnO-NPs
antitumor
ESC
NAC
oxidative stress and DNA damage
Online Access:https://www.dovepress.com/apoptosis-and-oxidative-stress-as-relevant-mechanisms-of-antitumor-act-peer-reviewed-article-IJN

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https://www.dovepress.com/apoptosis-and-oxidative-stress-as-relevant-mechanisms-of-antitumor-act-peer-reviewed-article-IJN

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