Angiopoietin-like 4 (ANGPTL4) Suppression Ameliorates Lupus Nephritis in MRL/lpr Mice by Inactivating NLRP3 Inflammasome and Inhibiting Inflammatory Response

Background: Lupus nephritis (LN) refers to the injury caused by systemic lupus erythematosus (SLE) involving the kidneys. A previous study identified angiopoietin-like protein 4 (ANGPTL4) as a novel urinary biomarker for tracking disease activity in LN.Objective: To investigate the detailed role and...

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Bibliographic Details
Main Authors: Dan Luo, Jun Li, Manli Hu, You Wang, Pei Pi, Min Ning, Jun Wu
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-09-01
Series:Iranian Journal of Immunology
Subjects:
Online Access:https://iji.sums.ac.ir/article_49463_3d0bd006690d69d751dd76089008668b.pdf