Pharmacodynamics and biodistribution of [195mPt]cisplatin(CISSPECT®) in head and neck squamous cell carcinoma

Pharmacodynamics and biodistribution of [195mPt]cisplatin(CISSPECT®) in head and neck squamous cell carcinoma

Abstract Background Cisplatin- based chemoradiotherapy is a crucial pillar in the treatment of HNSCC. The use of cisplatin comes with high toxicity rates as 35% of patients cannot sustain the planned dose while response is unpredictable. Unfortunately, there are no clinically applicable biomarkers t...

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Bibliographic Details
Main Authors: Reinout H. de Roest, Marijke Stigter van Walsum, Karlijn van der Schilden, Ruud H. Brakenhoff
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:EJNMMI Research
Subjects:
Head and neck squamous cell carcinoma
Cisplatin
[195m]Platinum
Cisspect
Online Access:https://doi.org/10.1186/s13550-024-01082-w

Internet

https://doi.org/10.1186/s13550-024-01082-w

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