DNA Damage Response and Cell Cycle Regulation in Pluripotent Stem Cells

DNA Damage Response and Cell Cycle Regulation in Pluripotent Stem Cells

Pluripotent stem cells (PSCs) hold great promise in cell-based therapy because of their pluripotent property and the ability to proliferate indefinitely. Embryonic stem cells (ESCs) derived from inner cell mass (ICM) possess unique cell cycle control with shortened G1 phase. In addition, ESCs have h...

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Bibliographic Details
Main Authors: Andy Chun Hang Chen, Qian Peng, Sze Wan Fong, Kai Chuen Lee, William Shu Biu Yeung, Yin Lau Lee
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Genes
Subjects:
DNA damage
cell cycle regulation
pluripotent stem cells (PSCs)
<i>FOXM1</i>
<i>SIRT1</i>
Online Access:https://www.mdpi.com/2073-4425/12/10/1548

Internet

https://www.mdpi.com/2073-4425/12/10/1548

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