Transcriptomic Landscape and Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Limbal Epithelial Progenitor Cells

Transcriptomic Landscape and Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Limbal Epithelial Progenitor Cells

Limbal stem cell deficiency (LSCD) is a complex, multifactorial disease affecting limbal epithelial progenitor cells (LEPC), which are essential for maintaining corneal stability and transparency. Human induced pluripotent stem cell-derived (hiPSC-) LEPC are a promising cell source for the treatment...

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Bibliographic Details
Main Authors: Naresh Polisetti, Julian Rapp, Paula Liang, Viviane Dettmer-Monaco, Felicitas Bucher, Jan Pruszak, Ursula Schlötzer-Schrehardt, Toni Cathomen, Günther Schlunck, Thomas Reinhard
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
induced pluripotent stem cells
limbal stem cells
limbal niche cells
melanocytes
limbal epithelial progenitor cells
corneal tissue engineering
Online Access:https://www.mdpi.com/2073-4409/11/23/3752

Internet

https://www.mdpi.com/2073-4409/11/23/3752

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