Metabolic phenotype of B cells from young and elderly HIV individuals

Abstract Background HIV infection induces inflammaging and chronic immune activation (IA), which are negatively associated with protective humoral immunity. Similar to HIV, aging is also associated with increased inflammaging and IA. The metabolic requirements of B cell responses in HIV infected (HI...

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Bibliographic Details
Main Authors: Daniela Frasca, Suresh Pallikkuth, Savita Pahwa
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-021-00245-w