Generation of two iPSC lines from vascular Ehlers-Danlos Syndrome (vEDS) patients carrying a missense mutation in COL3A1 gene

Generation of two iPSC lines from vascular Ehlers-Danlos Syndrome (vEDS) patients carrying a missense mutation in COL3A1 gene

Vascular Ehlers-Danlos Syndrome (vEDS) is an inherited connective tissue disorder caused by COL3A1 gene, mutations that encodes type III collagen, a crucial component of blood vessels. vEDS can be life-threatening as these patients can have severe internal bleeding due to arterial rupture. Here, we...

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Bibliographic Details
Main Authors: Amit Manhas, Dipti Tripathi, Chikage Noishiki, David Wu, Lu Liu, Karim Sallam, Jason T. Lee, Eri Fukaya, Nazish Sayed
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Stem Cell Research
Subjects:
vascular Ehlers-Danlos Syndrome
Induced pluripotent stem cells
COL3A1
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124001831

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http://www.sciencedirect.com/science/article/pii/S1873506124001831

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