Natural and Synthetic PPARγ Ligands in Tumor Microenvironment: A New Potential Strategy against Breast Cancer

Natural and Synthetic PPARγ Ligands in Tumor Microenvironment: A New Potential Strategy against Breast Cancer

Multiple lines of evidence indicate that activation of the peroxisome proliferator-activated receptor γ (PPARγ) by natural or synthetic ligands exerts tumor suppressive effects in different types of cancer, including breast carcinoma. Over the past decades a new picture of breast cancer as a complex...

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Bibliographic Details
Main Authors: Giuseppina Augimeri, Luca Gelsomino, Pierluigi Plastina, Cinzia Giordano, Ines Barone, Stefania Catalano, Sebastiano Andò, Daniela Bonofiglio
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
peroxisome proliferator-activated receptor gamma
PPARγ ligands
breast cancer
tumor microenvironment
cancer-associated adipocytes
cancer-associated fibroblasts
Online Access:https://www.mdpi.com/1422-0067/21/24/9721

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https://www.mdpi.com/1422-0067/21/24/9721

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