Tumor-derived exosomal HOTAIRM1 regulates SPON2 in CAFs to promote progression of lung adenocarcinoma

Tumor-derived exosomal HOTAIRM1 regulates SPON2 in CAFs to promote progression of lung adenocarcinoma

Abstract Objective SPON2 is one of the extracellular matrix proteins, which is closely related to the progression of a variety of tumors including non-small cell lung cancer (NSCLC), but its upstream regulation mechanism remains unclear. Our research aims to find the specific regulatory pathway of S...

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Bibliographic Details
Main Authors: Zhipeng Chen, Chengyu Bian, Jingjing Huang, Xiang Li, Liang Chen, Xueying Xie, Yang Xia, Rong Yin, Jun Wang
Format: Article
Language:English
Published: Springer 2022-09-01
Series:Discover Oncology
Subjects:
Lung adenocarcinoma
Tumour microenvironment
CAFs
Exosomes
SPON2
Online Access:https://doi.org/10.1007/s12672-022-00553-7

Internet

https://doi.org/10.1007/s12672-022-00553-7

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