Determination of ED50 and time to effectiveness for intrathecal hydromorphone in laboring patients using Dixon’s up-and-down sequential allocation method

Determination of ED50 and time to effectiveness for intrathecal hydromorphone in laboring patients using Dixon’s up-and-down sequential allocation method

Abstract Background With the increasing occurrence of drug shortages, understanding the pharmacokinetics of alternative intrathecal opioid administration has gained importance. In particular, additional data are needed to comprehensively evaluate the analgesic properties of intrathecal hydromorphone...

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Bibliographic Details
Main Authors: Vikas O’Reilly-Shah, Grant C Lynde
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Anesthesiology
Subjects:
Hydromorphone
Analgesics
Opioid
Labor
Obstetric
Intrathecal
Online Access:http://link.springer.com/article/10.1186/s12871-018-0603-8

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http://link.springer.com/article/10.1186/s12871-018-0603-8

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