In Vitro and Ex Vivo Evaluation of Fluocinolone Acetonide–Acitretin-Coloaded Nanostructured Lipid Carriers for Topical Treatment of Psoriasis

In Vitro and Ex Vivo Evaluation of Fluocinolone Acetonide–Acitretin-Coloaded Nanostructured Lipid Carriers for Topical Treatment of Psoriasis

Psoriasis is chronic autoimmune disease that affects 2–5% of the global population. Fluocinolone acetonide (FLU) and acitretin (ACT) are widely used antipsoriatic drugs that belong to BCS classes II and IV, respectively. FLU exhibits side effects, such as skin irritation and a burning sensation. ACT...

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Bibliographic Details
Main Authors: Hassan Raza, Shefaat Ullah Shah, Zakir Ali, Atif Ullah Khan, Irfa Basharat Rajput, Arshad Farid, Mohammed Al Mohaini, Abdulkhaliq J. Alsalman, Maitham A. Al Hawaj, Saima Mahmood, Abid Hussain, Kifayat Ullah Shah
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Gels
Subjects:
fluocinolone acetonide
acitretin
nanostructured lipid carrier
bioavailability
occlusive effect
entrapment efficiency
Online Access:https://www.mdpi.com/2310-2861/8/11/746

Internet

https://www.mdpi.com/2310-2861/8/11/746

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