The Antidepressant-like Activity and Cognitive Enhancing Effects of the Combined Administration of (<i>R</i>)-Ketamine and LY341495 in the CUMS Model of Depression in Mice Are Related to the Modulation of Excitatory Synaptic Transmission and LTP in the PFC

(<i>S</i>)-Ketamine is the first rapid-acting antidepressant drug (RAAD) introduced for the treatment of depression. However, research is still being carried out on the search for further RAADs that will be not only effective but also safe to use. Recent data have indicated that the comb...

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Bibliographic Details
Main Authors: Agnieszka Pałucha-Poniewiera, Bartosz Bobula, Anna Rafało-Ulińska
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/2/288