Mucosal-associated invariant T cells in patients with axial spondyloarthritis

Mucosal-associated invariant T cells in patients with axial spondyloarthritis

BackgroundSeveral studies implicate Th17-cells and its cytokine (IL-17) in disease pathogenesis of spondyloarthritis (SpA), with available evidence supporting a pathogenic role of CD8+ T-cells. However, data on the involvement of CD8+ mucosal-associated invariant T-cells (MAIT) and their phenotypic...

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Bibliographic Details
Main Authors: Rienk Gerben van der Meer, Anneke Spoorenberg, Elisabeth Brouwer, Berber Doornbos-van der Meer, Annemieke M. H. Boots, Suzanne Arends, Wayel H. Abdulahad
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
axial spondyloarthritis
immunology
MAIT cells
Granzyme A
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1128270/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1128270/full

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