Highly-purified rapidly expanding clones, RECs, are superior for functional-mitochondrial transfer

Highly-purified rapidly expanding clones, RECs, are superior for functional-mitochondrial transfer

Abstract Background Mitochondrial dysfunction caused by mutations in mitochondrial DNA (mtDNA) or nuclear DNA, which codes for mitochondrial components, are known to be associated with various genetic and congenital disorders. These mitochondrial disorders not only impair energy production but also...

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Bibliographic Details
Main Authors: Jiahao Yang, Lu Liu, Yasuaki Oda, Keisuke Wada, Mako Ago, Shinichiro Matsuda, Miho Hattori, Tsukimi Goto, Yuki Kawashima, Yumi Matsuzaki, Takeshi Taketani
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells (MSCs)
Rapidly expanding clones (RECs)
Mitochondrial transfer
Mitochondrial dysfunction
Online Access:https://doi.org/10.1186/s13287-023-03274-y

Internet

https://doi.org/10.1186/s13287-023-03274-y

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