Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets

Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets

Abstract Background Pancreatic β-cells require a constant supply of zinc to maintain normal insulin secretory function. Following co-exocytosis with insulin, zinc is replenished via the Zrt- and Irt-like (ZIP; SLC39A) family of transporters. However the ZIP paralogues of particular importance for zi...

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Bibliographic Details
Main Authors: Rebecca Lawson, Wolfgang Maret, Christer Hogstrand
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Genomics
Subjects:
Type 2 diabetes
Zinc
ZIP
SLC39A
Systematic review
Expression data
Online Access:http://link.springer.com/article/10.1186/s12864-017-4119-2

Internet

http://link.springer.com/article/10.1186/s12864-017-4119-2

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