Radiosensitizing Effect of Trabectedin on Human Soft Tissue Sarcoma Cells

Radiosensitizing Effect of Trabectedin on Human Soft Tissue Sarcoma Cells

Trabectedin is used for the treatment of advanced soft tissue sarcomas (STSs). In this study, we evaluated if trabectedin could enhance the efficacy of irradiation (IR) by increasing the intrinsic cell radiosensitivity and modulating tumor micro-environment in fibrosarcoma (HS 93.T), leiomyosarcoma...

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Bibliographic Details
Main Authors: Mauro Loi, Giulia Salvatore, Michele Aquilano, Daniela Greto, Cinzia Talamonti, Viola Salvestrini, Maria Elena Melica, Marianna Valzano, Giulio Francolini, Mariangela Sottili, Costanza Santini, Carlotta Becherini, Domenico Andrea Campanacci, Monica Mangoni, Lorenzo Livi
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
soft tissue sarcoma
trabectedin
radiation
radiosensitizers
Online Access:https://www.mdpi.com/1422-0067/23/22/14305

Internet

https://www.mdpi.com/1422-0067/23/22/14305

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