Microglia/macrophages require vitamin D signaling to restrain neuroinflammation and brain injury in a murine ischemic stroke model

Microglia/macrophages require vitamin D signaling to restrain neuroinflammation and brain injury in a murine ischemic stroke model

Abstract Vitamin D deficiency is associated with worse clinical outcomes after ischemic stroke; nevertheless, the pathophysiological mechanisms remain largely unexplored. In this study, we characterized the molecular mechanisms of how vitamin D signaling modulated stroke progression in male mouse is...

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Bibliographic Details
Main Authors: Pan Cui, Wanting Lu, Junjie Wang, Fei Wang, Xiyue Zhang, Xiaodan Hou, Fang Xu, Yan Liang, Guoliang Chai, Junwei Hao
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Neuroinflammation
Subjects:
Acute ischemic stroke
Vitamin D deficiency
Vitamin D receptor
Microglia/macrophages
Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-023-02705-0

Internet

https://doi.org/10.1186/s12974-023-02705-0

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