Evidence for G‐Protein–Coupled Estrogen Receptor as a Pronatriuretic Factor

Evidence for G‐Protein–Coupled Estrogen Receptor as a Pronatriuretic Factor

Background The novel estrogen receptor, G‐protein–coupled estrogen receptor (GPER), is responsible for rapid estrogen signaling. GPER activation elicits cardiovascular and nephroprotective effects against salt‐induced complications, yet there is no direct evidence for GPER control of renal Na+ handl...

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Bibliographic Details
Main Authors: Eman Y. Gohar, Elizabeth M. Daugherty, Jeffrey O. Aceves, Randee Sedaka, Ijeoma E. Obi, J. Miller Allan, Reham H. Soliman, Chunhua Jin, Carmen De Miguel, Sarah H. Lindsey, Jennifer S. Pollock, David M. Pollock
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
endothelin 1
estrogen
GPER
hypertension
kidney
sodium excretion
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.015110

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.015110

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