Causal association of epigenetic aging and osteoporosis: a bidirectional Mendelian randomization study

Causal association of epigenetic aging and osteoporosis: a bidirectional Mendelian randomization study

Abstract Background The relationship between aging and osteoporosis is well established. However, the relationship between the body's physiological age, i.e. epigenetic age, and osteoporosis is not known. Our goal is to analyze the bidirectional causal relationship between epigenetic clocks and...

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Bibliographic Details
Main Authors: Xinyu Liang, Wei Shi, Xinglong Zhang, Ran Pang, Kai Zhang, Qian Xu, Chunlei Xu, Xin Wan, Wenhao Cui, Dong Li, Zhaohui Jiang, Zhengxuan Liu, Hui Li, Huafeng Zhang, Zhijun Li
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Medical Genomics
Subjects:
Mendelian randomization
Epigenetic age
Osteoporosis
Causal association
Genome-wide association study
Online Access:https://doi.org/10.1186/s12920-023-01708-3

Internet

https://doi.org/10.1186/s12920-023-01708-3

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