Scientific rationale for a higher dose of nusinersen

Scientific rationale for a higher dose of nusinersen

Abstract Objective The long‐term favorable safety profile of nusinersen provides an opportunity to consider a higher dose. We report on the relationships between nusinersen cerebrospinal fluid (CSF) exposure, biomarker levels, and clinical efficacy. Methods The analyses used data from the CS3A and E...

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Bibliographic Details
Main Authors: Richard S. Finkel, Monique M. Ryan, Samuel Ignacio Pascual Pascual, John W. Day, Eugenio Mercuri, Darryl C. De Vivo, Richard Foster, Jacqueline Montes, Juliana Gurgel‐Giannetti, Drew MacCannell, Zdenek Berger
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51562

Internet

https://doi.org/10.1002/acn3.51562

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