Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity

Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity

Liver fibrosis is a critical complication of obesity-induced fatty liver disease. Wnt1 inducible signaling pathway protein 1 (WISP1/CCN4), a novel adipokine associated with visceral obesity and insulin resistance, also contributes to lung and kidney fibrosis. The aim of the present study was to inve...

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Bibliographic Details
Main Authors: Olga Pivovarova-Ramich, Jennifer Loske, Silke Hornemann, Mariya Markova, Nicole Seebeck, Anke Rosenthal, Frederick Klauschen, José Pedro Castro, René Buschow, Tilman Grune, Volker Lange, Natalia Rudovich, D. Margriet Ouwens
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
WISP-1/CCN4
CCN proteins
adipokine
obesity
liver
fibrosis
Online Access:https://www.mdpi.com/2073-4409/10/5/1048

Internet

https://www.mdpi.com/2073-4409/10/5/1048

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