Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.

Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.

UFM1 is a member of the ubiquitin like protein family. While the enzymatic cascade of UFM1 conjugation has been elucidated in recent years, the biological function remains largely unknown. In this report we demonstrate that the recently identified C20orf116, which we name UFM1-binding protein 1 cont...

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Bibliographic Details
Main Authors: Katleen Lemaire, Rodrigo F Moura, Mikaela Granvik, Mariana Igoillo-Esteve, Hans E Hohmeier, Nico Hendrickx, Christopher B Newgard, Etienne Waelkens, Miriam Cnop, Frans Schuit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3071830?pdf=render

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http://europepmc.org/articles/PMC3071830?pdf=render

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