Epigenetic regulatory mechanism of ADAMTS12 expression in osteoarthritis
Abstract Background Osteoarthritis (OA) is a degenerative joint disease with lacking effective prevention targets. A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAMTS12) is a member of the ADAMTS family and is upregulated in OA pathologic tissues with no fully understood molecu...
Main Authors: | Shu Yang, Xuanping Zhou, Zhen Jia, Mali Zhang, Minghao Yuan, Yizhao Zhou, Jing Wang, Duo Xia |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s10020-023-00661-2 |
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