Carboplatin dose calculations for patients with lung cancer: significant dose differences found depending on dosing equation choice

Abstract Background Carboplatin is the backbone cytotoxic agent for many chemotherapy regimens for lung cancer. Dosing of carboplatin is complicated due to its relationship to renal function and narrow therapeutic index. Overestimation of renal function may lead to supratherapeutic dosing and toxici...

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Bibliographic Details
Main Authors: Seçkin Akgül, Bryan A. Chan, Peter M. Manders
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09885-7