Radioiodinated phenylalkyl malonic acid derivatives as pH-sensitive SPECT tracers.
INTRODUCTION: In vivo pH imaging has been a field of interest for molecular imaging for many years. This is especially important for determining tumor acidity, an important driving force of tumor invasion and metastasis formation, but also in the process of apoptosis. METHODS: 2-(4-[(123)I]iodophene...
Main Authors: | Matthias Bauwens, Marijke De Saint-Hubert, Jan Cleynhens, Laura Brams, Ellen Devos, Felix M Mottaghy, Alfons Verbruggen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3374791?pdf=render |
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