Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5

Summary: The germinal center (GC) response is critical for generating high-affinity humoral immunity and immunological memory, which forms the basis of successful immunization. Control of the GC response is thought to require follicular regulatory T (Tfr) cells, a subset of suppressive Foxp3+ regula...

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Dettagli Bibliografici
Autori principali: Ine Vanderleyden, Sigrid C. Fra-Bido, Silvia Innocentin, Marisa Stebegg, Hanneke Okkenhaug, Nicola Evans-Bailey, Wim Pierson, Alice E. Denton, Michelle A. Linterman
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2020-01-01
Serie:Cell Reports
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124719317413