Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma

Abstract Background Galectin-3 is a 32 kDa protein secreted by macrophages involved in processes such as cell activation, chemotaxis and phagocytosis. Galectin-3 has previously been shown to improve the ability of airway macrophages to ingest apoptotic cells (efferocytosis) in chronic obstructive pu...

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Bibliographic Details
Main Authors: Melanie Erriah, Kavita Pabreja, Michael Fricker, Katherine J. Baines, Louise E. Donnelly, Johan Bylund, Anna Karlsson, Jodie L. Simpson
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-018-0967-9