Effects of hypoxic condition on osteogenic differentiation of human periodontal ligament cells via hypoxia in⁃ ducible factor⁃1α

Effects of hypoxic condition on osteogenic differentiation of human periodontal ligament cells via hypoxia in⁃ ducible factor⁃1α

Objective To investigate the effects of hypoxia on osteogenic differentiation of periodontal ligament cells (PDLCs) and the role of hypoxia inducible factor⁃1α (HIF⁃1α) in this process. Methods Human PDLCs were iso⁃ lated and identified by checking the expression of vimentin and cytokeratin. PDLCs...

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Bibliographic Details
Main Authors: PANG Jingwen, WU Yalin, XU Ting, ZHUANG Xiumei
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2017-08-01
Series:口腔疾病防治
Subjects:
Periodontitis
Periodontal ligament cells
Hypoxia
Osteogenic differentiation
Hypoxia induc⁃ ible factor⁃1α
Online Access:http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2017.08.003

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http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2017.08.003

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