Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis

Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis

Loss-of-function mutations in the human <i>ICK</i> (intestinal cell kinase) gene cause dysfunctional primary cilia and perinatal lethality which are associated with human ciliopathies. The enzyme that we herein call CAPK (ciliopathy-associated protein kinase) is a serine/threonine protei...

Full description

Bibliographic Details
Main Authors: Yoon Seon Oh, Eric J. Wang, Casey D. Gailey, David L. Brautigan, Benjamin L. Allen, Zheng Fu
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
primary cilia
ciliopathy
intestinal cell kinase
ciliopathy-associated protein kinase
ciliogenesis
kinesin family member 3A
and phosphorylation
Online Access:https://www.mdpi.com/2073-4409/8/7/677

Internet

https://www.mdpi.com/2073-4409/8/7/677

Similar Items