Development and validation of an LC-MS/MS method for pharmacokinetic study of lobetyolin in rats
Abstract A simple and selective liquid chromatography tandem with mass spectrometry (LC-MS/ MS) method for quantification of lobetyolin in rat plasma was developed and validated. Chromatographic separation was achieved on a Thermo ODS C18 reversed-phase column using 0.1% aqueous formic acid-methanol...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
2023-01-01
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Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100870&tlng=en |