Leader gene identification for digestive system cancers based on human subcellular location and cancer-related characteristics in protein–protein interaction networks

Stomach, liver, and colon cancers are the most common digestive system cancers leading to mortality. Cancer leader genes were identified in the current study as the genes that contribute to tumor initiation and could shed light on the molecular mechanisms in tumorigenesis. An integrated procedure wa...

Full description

Bibliographic Details
Main Authors: Hongwei Chen, Zherou Rong, Luanfeng Ge, Hongzheng Yu, Chao Li, Manyi Xu, Zihan Zhang, Junjie Lv, Yuehan He, Wan Li, Lina Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.919210/full