PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

PD-1 and TIGIT Are Highly Co-Expressed on CD8+ T Cells in AML Patient Bone Marrow

Despite the great success of immune-checkpoint inhibitor (ICI) treatment for multiple cancers, evidence for the clinical use of ICIs in acute myeloid leukemia (AML) remains inadequate. Further exploration of the causes of immune evasion in the bone marrow (BM) environment, the primary leukemia site,...

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Bibliographic Details
Main Authors: Ling Xu, Lian Liu, Danlin Yao, Xiangbo Zeng, Yikai Zhang, Jing Lai, Jun Zhong, Xianfeng Zha, Runhui Zheng, Yuhong Lu, Minming Li, Zhenyi Jin, Sudheendra Hebbar Subramanyam, Shaohua Chen, Xin Huang, Yangqiu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
PD-1
TIGIT
acute myeloid leukemia
immune-checkpoints
T cell
bone marrow
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.686156/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.686156/full

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