Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport

Nuclear transport receptors of the karyopherin superfamily of proteins transport macromolecules from one compartment to the other and are critical for both cell physiology and pathophysiology. The nuclear transport machinery is tightly regulated and essential to a number of key cellular processes si...

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Bibliographic Details
Main Authors: Friederike K. Kosyna, Reinhard Depping
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/7/11/221