Early detection of the aflatoxin B1 mutational fingerprint: A diagnostic tool for liver cancer

Using duplex-consensus sequencing technology, we recently identified the characteristic high-resolution mutational spectrum of the liver carcinogen aflatoxin B1 in a mouse model, many months before aflatoxin-induced tumors are detectable. The diagnostic power of this spectrum is then demonstrated by...

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Bibliographic Details
Main Authors: Bogdan I. Fedeles, Supawadee Chawanthayatham, Robert G. Croy, Gerald N. Wogan, John M. Essigmann
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1329693