Sclerostin: clinical insights in muscle–bone crosstalk

Sclerostin, a protein encoded by the sclerostin ( SOST ) gene, is mostly expressed in osteocytes. First described in the pathogenesis of three disorders, sclerosteosis, van Buchem’s disease, and craniodiaphyseal dysplasia, sclerostin has been identified as an important regulator of bone homeostasis,...

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Bibliographic Details
Main Authors: Antimo Moretti, Giovanni Iolascon
Format: Article
Language:English
Published: SAGE Publishing 2023-08-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605231193293