Human Cytomegalovirus (HCMV) Glycoprotein gB Promotes Virus Entry In <italic toggle="yes">Trans</italic> Acting as the Viral Fusion Protein Rather than as a Receptor-Binding Protein

ABSTRACT Human cytomegalovirus (HCMV) glycoproteins gB and gH/gL are both necessary and sufficient for cell-cell fusion. However, it is not clear what roles these glycoproteins play in virus entry, whether acting directly in membrane fusion or in binding receptors. With other herpesviruses, it appea...

Full description

Bibliographic Details
Main Authors: Paul T. Wille, Todd W. Wisner, Brent Ryckman, David C. Johnson
Format: Article
Language:English
Published: American Society for Microbiology 2013-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00332-13