Where are we in the implementation of tissue-specific epigenetic clocks?

Introduction: DNA methylation clocks presents advantageous characteristics with respect to the ambitious goal of identifying very early markers of disease, based on the concept that accelerated ageing is a reliable predictor in this sense.Methods: Such tools, being epigenomic based, are expected to...

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Main Authors: Claudia Sala, Pietro Di Lena, Danielle Fernandes Durso, Italo Faria do Valle, Maria Giulia Bacalini, Daniele Dall’Olio, Claudio Franceschi, Gastone Castellani, Paolo Garagnani, Christine Nardini
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Bioinformatics
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Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2024.1306244/full