Plasma metabolites of aromatic amino acids associate with clinical severity and gut microbiota of Parkinson’s disease

Abstract Gut microbial proteolytic metabolism has been reportedly altered in Parkinson’s disease (PD). However, the circulating aromatic amino acids (AAA) described in PD are inconsistent. Here we aimed to investigate plasma AAA profiles in a large cohort of PD patients, and examine their correlatio...

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Bibliographic Details
Main Authors: Szu-Ju Chen, Yu-Jun Wu, Chieh-Chang Chen, Yu-Wei Wu, Jyh-Ming Liou, Ming-Shiang Wu, Ching-Hua Kuo, Chin-Hsien Lin
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00612-y