Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data

Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data

Abstract Background Brain volume has been widely studied in the neuroimaging field, since it is an important and heritable trait associated with brain development, aging and various neurological and psychiatric disorders. Genome-wide association studies (GWAS) have successfully identified numerous a...

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Bibliographic Details
Main Authors: Hung Mai, Jingxuan Bao, Paul M. Thompson, Dokyoon Kim, Li Shen
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Bioinformatics
Subjects:
Genetic variation
Gene expression
Brain imaging
Imaging genomic association
Brain volume
Online Access:https://doi.org/10.1186/s12859-022-04947-w

Internet

https://doi.org/10.1186/s12859-022-04947-w

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