Profiling the role of m6A effectors in the regulation of pluripotent reprogramming

Abstract The N6-methyladenosine (m6A) RNA modification plays essential roles in multiple biological processes, including stem cell fate determination. To explore the role of the m6A modification in pluripotent reprogramming, we used RNA-seq to map m6A effectors in human iPSCs, fibroblasts, and H9 ES...

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Bibliographic Details
Main Authors: Wenjun Wang, Lei Zhou, Hui Li, Tingge Sun, Xue Wen, Wei Li, Miguel A. Esteban, Andrew R. Hoffman, Ji-Fan Hu, Jiuwei Cui
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-024-00597-6