A Trickster in Disguise: Hyaluronan’s Ambivalent Roles in the Matrix

Hyaluronan (HA) is a simple but diverse glycosaminoglycan. It plays a major role in aging, cellular senescence, cancer, and tissue homeostasis. In which way HA affects the surrounding tissues greatly depends on the molecular weight of HA. Whereas high molecular weight HA is associated with homeostas...

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Bibliographic Details
Main Authors: Lena Bohaumilitzky, Ann-Kathrin Huber, Eva Maria Stork, Simon Wengert, Franziska Woelfl, Heike Boehm
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00242/full