C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cells

C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cells

Abstract The transcription factor C/EBPβ is a master regulator of mammary gland development and tissue remodelling during lactation. The CEBPB-mRNA is translated into three distinct protein isoforms named C/EBPβ-LAP1, -LAP2 and -LIP that are functionally different. The smaller isoform LIP lacks the...

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Main Authors: Britt A. Sterken, Tobias Ackermann, Christine Müller, Hidde R. Zuidhof, Gertrud Kortman, Alejandra Hernandez-Segura, Mathilde Broekhuis, Diana Spierings, Victor Guryev, Cornelis F. Calkhoven
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00372-z

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https://doi.org/10.1038/s41523-021-00372-z

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