Increasing the Editing Efficiency of the MS2-ADAR System for Site-Directed RNA Editing

Increasing the Editing Efficiency of the MS2-ADAR System for Site-Directed RNA Editing

Site-directed RNA editing (SDRE) technologies have great potential in gene therapy. Our group has developed a strategy to redirect exogenous adenosine deaminases acting on RNA (ADARs) to specific sites by making editable structures using antisense RNA oligonucleotides. Improving the editing efficien...

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Bibliographic Details
Main Authors: Jiarui Li, Tomoko Oonishi, Guangyao Fan, Matomo Sakari, Toshifumi Tsukahara
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Applied Sciences
Subjects:
RNA editing
adenosine deaminase acting on RNA
MS2 system
Online Access:https://www.mdpi.com/2076-3417/13/4/2383

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https://www.mdpi.com/2076-3417/13/4/2383

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