Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Abstract Background Enhancers are distal cis-regulatory elements that control gene expression. Despite an increasing appreciation of the importance of enhancers in cellular function and disease, our knowledge of enhancer-regulated transcription is very limited. Nascent RNA sequencing technologies, s...

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Bibliographic Details
Main Authors: Jing Wang, Yue Zhao, Xiaofan Zhou, Scott W. Hiebert, Qi Liu, Yu Shyr
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-018-5016-z