A triple-masked, two-center, randomized parallel clinical trial to assess the superiority of eight weeks of grape seed flour supplementation against placebo for weight loss attenuation during perioperative period in patients with cachexia associated with colorectal cancer: a study protocol

BackgroundProgressive, involuntary weight and lean mass loss in cancer are linked to cachexia, a prevalent syndrome in gastrointestinal malignancies that impacts quality of life, survival and postoperative complications. Its pathophysiology is complex and believed to involve proinflammatory cytokine...

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Bibliografski detalji
Glavni autori: Felipe Aguiar Pupo Seabra Malta, Daniela Caetano Gonçalves
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2024-01-01
Serija:Frontiers in Endocrinology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fendo.2023.1146479/full