Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs

<p>Abstract</p> <p>Background</p> <p>Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2)-mediated survival signaling is critical to endothelial cell survival, maintenance of the vasculature and alveolar structure and regeneration of lung tissue. Reduc...

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Bibliographic Details
Main Authors: Stevenson Christopher S, Arunachalam Gnanapragasam, Edirisinghe Indika, Marwick John A, MacNee William, Kirkham Paul A, Rahman Irfan
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/7/1/11