PDE 7 inhibitors: new potential drugs for the therapy of spinal cord injury.

BACKGROUND: Primary traumatic mechanical injury to the spinal cord (SCI) causes the death of a number of neurons that to date can neither be recovered nor regenerated. During the last years our group has been involved in the design, synthesis and evaluation of PDE7 inhibitors as new innovative drugs...

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Bibliographic Details
Main Authors: Irene Paterniti, Emanuela Mazzon, Carmen Gil, Daniela Impellizzeri, Valle Palomo, Myriam Redondo, Daniel I Perez, Emanuela Esposito, Ana Martinez, Salvatore Cuzzocrea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3031524?pdf=render